Long Lost Night Dapoxetine Tablets
Long Lost Night 4 TABS
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Long Lost Night Dapoxetine Tablets in Pakistan
Long Lost Night Dapoxetine Tablets a part of the physiological process of erection includes the parasympathetic systema nervosum causing the discharge of gas (NO) within the Corpus cavernosum of the penis. No binds to the receptors of the enzyme guanylate cyclase which results in increased degrees of cyclic guanosine monophosphate (cGMP). Resulting in Smooth Muscle Relaxation (vasodilation) inside the corpuscavernosum, leading to improved inflow of blood and an erection.
Sildenafil may be a effective and selective inhibitor of cGMP specific phosphodiesterase kind 5 (PDE5) which is responsible for the degradation of cGMP within the corpus cavernosum. The molecular structure of Sildenafil id almost like that of cGMP and acts as a competitive binding agent of PDE5 I within the corpus cavernosum, ensuing in additional cGMP and better erections.
Long Lost Night Sildenafil & Dapoxetine 60mg
Long lost night tablet dapoxetine 60mg tablet is rapidly absorbs after oral administration with a peak plasma concentration (tmaxx) occurring between 1.4 and 2.0 hours. This can be follows by a rapid decline in plasma concentration, to about 5% of peak increased proportionately with doses up to 100 mg.
The mean initial half lifetime of dapoxetine after one dose is 0.5 to 0.8 hours and this decreased slightly to 0.4 to 0.6 hours after multiple doses for 6 days. The terminal half-life of dapoxetine was 15 to 19 pairs after one dose and 20 to 24 after multiple doses. Dapoxetine undergoes hepatic metabolism to 2 metabolites,
Dapoxetine tablets exhibits its efficacy by primarily inhibiting the reuptake of the serotonin transporter. It had been also shown to bind and inhibit the reuptake transporters of dopamine & norepinephrine.
The onset of action: 60 minutes
Duration: 2-4 hours
Absorption: Rapid, slower with a high-fat meal
Distribution: Vdss: 105 l
Protein binding, plasma: 96% metabolism: hepatic via cyp3a4 (major and cyp2c9 ( minor route)
Half life elimination: 4 hours
Time to peak: 30-120 minutes; delayed by hour with a high-fat meal.
How to Take Long Lost Night Tablet: Take 1 Tablet 1-2 Hours before sexual intercourse with warm water…